Curcumin C3 Complex
- Research activities and institutions where Curcumin C3 Is Used
- Pharmacology
- Anti Cancer Action
- Anticancer, Antitumor and Antiproliferative
- M. D. Anderson News Release 10/14/05
- Research methods
- Anti Inflammatory Action
- Wound Healing
- Immunomudulation
- Curcumin and Alzheimer’s Disease
- Curcumin and Green Tea
- Boswellin Reduce Joint Pain and Arthritis
- Conclusion
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Turmeric (Curcuma Longa)
family of Zingiberaceae) a Perennial herbal plant
| Category: Science & Technology |
| Tags: Curcumin Extract | Many health benefits of turmeric root | Tumeric health inflammation cancer Alzheimer's cholesterol antioxidant hers botanicals spices adventure medicine |
Introduction Curcumin (Turmeric Extract):
Curcumin (Turmeric Extract) is from the roots of the turmeric plant (Extract dietary supplements rather than the turmeric). Turmeric is an ancient Indian spice and a traditional remedy that has been used as a medicine, condiment and flavoring. As per Indian Ayurvedic text turmeric can be taken on a daily basis to improve body immunity. Its effects on Alzheimer’s, Arthritis, Cancer, Cholesterol, Weight loss, Diabetes, skin wrinkles, Anti Ageing, and supports healthy immune inflammatory and other health problems. |  |
| - Curcumin is very useful in joint related concerns |
| - Curcumin helps maintain a normal cholesterol and a healthy heart. |
| - Curcumin is very helpful as a digestive support. |
| - Curcumin is extremely helpful in liver protection. |
| - Curcumin is also used in controling obesity. |
| - Curcumin induces the flow of bile, which breaks down fats. |
| - Curcumin acts as an anti-inflammatory agent that relieves the aches and pains associated with arthritis. |
Curcumin C3 Complex® enjoys a special place among curcumin extracts. The name C3 Complex has reference to its three main chemical compounds – Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin – collectively known as Curcuminoids. Patented for its unique composition ratio is described as a Bioprotectant. Perhaps better understood as a “Super Anti-oxidant”, C3 Complex provides optimal protection and integrity to biological systems.
A. BOTANICAL INFORMATION Of Curcumin Turmeric
Family : Zingiberaceae
Genus : Curcuma
Most common species Curcuma longa
Number of Curcuma Species 70
Part used Rhizome (Root)
Names in Other Languages : Habitat : Southern Asia and Polynesia
| Hindi | : | Haridra |
| Urdu | : | Haldi |
| Telugu | : | Passpu |
| Mandarin | : | Jiang Huang |
| Japanese | : | Kyoo |
| Tahitian | : | Re’a |
| Marquesan | : | Ena |
| : | Samoan, Tongan Ago, Ango | |
| Cook Islands | : | Renga |
Hawaiian ‘Olena (Curcuma domestica)
Literal English Translation
“Yellow Ginger”
Maude Grieve provides the following botanical information:
More search help : Google Health search
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Here's yet another thing that curcumin does: it has been proven to increase the solubility of bile, that is, it makes it dissolve more easily. Bile is a fluid produced by the liver that helps you digest fats, but when the liver or gall bladder becomes congested, this fluid can harden, forming gall stones. Taking turmeric daily has been shown to eliminate up to 80% of gall stones in just a few weeks. It will also help prevent them from forming in the first place.
Turmeric-Curcumin is also a COX 2 inhibitor, that is, it inhibits the action of an enzyme called cyclooxygenase-2 which is partly responsible for the pain of arthritis, so it can be used as an effective (and much safer substitute for the arthritis drug “Celebrex“ and other similar drugs.The active ingredient curcumin which decreases amounts of prostaglandins (involved in the transmission of pain signals) and stimulates the adrenal glands to release natural cortisone, which also reduces inflammation.
In fact, curcumin has proven to be almost as effective as cortisone in the treatment of some kinds of inflammation. In short, it's a safe and effective pain killer so reach for it instead of aspirin or other pain killers (but remember to look for the source of your pain as well).
Take advantage of its pain/inflammation relieving abilities for things like arthritis, bunions, bursitis, tendinitis, carpal tunnel syndrome (inflammation of the wrist), gout, headaches of all sorts, geographic tongue (tongue inflammation), etc. It can be taken as a tea, in capsules, as a tincture, or applied directly to the painful area as a poultice or fomentation. Use your imagination. Also take a small amount daily (a teaspoon or so) and get on a good cleansing program to help keep the problem from coming back.
One study in Thailand showed that taking curcumin is good for relieving the pain of ulcers. In Ayurveda, an East Indian system of medicine, physicians make a paste of two parts turmeric and one part salt to apply as a poultice to swollen areas. Some also add some ginger to this mixture.
Dr. Michael Murray, N.D., co-author of the Encyclopedia of Natural Medicine, calls curcumin one of nature's most powerful anti-edemic and anti-inflammatory agents. So use it both internally and externally wherever there is abnormal swelling.
Curcumin also thins the blood and helps prevent blood clots. This is very important in preventing such things as strokes, heart attacks, thrombosis (blood clots inside a vein), etc.
Here's yet another thing that curcumin does: it has been proven to increase the solubility of bile, that is, it makes it dissolve more easily. Bile is a fluid produced by the liver that helps you digest fats, but when the liver or gall bladder becomes congested, this fluid can harden, forming gall stones. Taking curcumin daily has been shown to eliminate up to 80% of gall stones in just a few weeks. It will also help prevent them from forming in the first place.
It also contains several compounds that protect the liver from damage.
Curcumin is rich in antioxidants like vitamins A (carotenoids), C, and E and others (yes, curcumin is an antioxidant too) which help prevent a great many complaints associated with old age like cataracts.
Curcumin also inhibits many common problem types of fungi and is useful for athlete's foot. Try adding a teaspoon or two to a hot footbath (soaking your feet in a small tub or pan of hot water).
It kills various parasites as well, like lice and scabies (microscopic parasitic mites that infect the skin). Make a paste and apply it to all the affected areas each day for a couple of weeks or until the problem is cured. For lice, it's also a good idea to boil your clothes and bedding to prevent reinfection.
Take Curcumin to get rid of other parasites too, especially nematodes. Turmeric contains four anti-parasitic chemicals, each of which is not effective alone, but when combined, they make a strong worm-killing cocktail. This phenomenon is called synergy and you will never find it in any pharmaceutical drugs since they are all isolated chemicals. Only God's herbs have this advantage.
Curcumin helps the body to use insulin more efficiently, making it great to use for both type #1 and type #2 diabetes.
Various studies show that it can help heal wounds (apply as powder or use the tea as a wash) and even help fight Alzheimer's Disease and Multiple Sclerosis (MS) (taken internally).
And last but not least, Curcumin has been proven effective at destroying certain types of cancer cells. The researchers at the University of Texas MD Anderson Cancer Center conducted a study which showed that when curcumin was introduced into cell cultures containing multiple myeloma (a type of cancer), it stopped the cancer cells from reproducing and those that were left died. Previous research indicates that it may be effective in fighting other cancers as well (I'm not at all surprised). And best of all, it has no known side effects, even in very large amounts.
Research activities and institutions where Curcumin C3 Is Used
Pharmacology
Anti Cancer Action
The compound curcumin is responsible for the yellowish-orange color and distinctive smell of tumeric. Curcumin is more than just a simple pigment. Researchers at the cancer center in Houston reported that curcumin stops laboratory strains of melanoma from proliferating and causes the cancer cells to commit suicide. The findings are so dramatic that human clinical trials are already underway testing curcumin's ability to retard the growth of both pancreatic and breast cancer, and animal studies of its effects on melanoma will begin shortly.
So far, the researchers have found that curcumin has had a positive effect on every tumor market they have tried. By the way, all of these studies involve the use of daily oral curcumin supplements that are readily available today.
Anticancer, Antitumor and Antiproliferative
M. D. Anderson News Release 10/14/05
At M. D. Anderson, for example, dramatic results from laboratory studies have led to two ongoing Phase I human clinical trials, testing the ability of daily capsules of curcumin powder to retard growth of pancreatic cancer and multiple myeloma. Another Phase I trial was done for patients with breast cancer, and given this news of curcumin's activity in melanoma, animal studies will soon begin, Aggarwal says. While researchers had thought curcumin primarily has anti-inflammatory properties, the growing realization that cancer can result from inflammation has spurred mounting interest in the spice as an anti-cancer agent. Curcumin had any effect on patients with pancreatic cancer, which is difficult to treat successfully.
Oral administration of curcumin has been shown in several earlier studies to inhibit oral, forestomach, duodenal and colon cancer. One study also reports the cytotoxicity of curcuminoids against human ovarian cancer OVCAR-3 cells. Another study was directed towards oral cancer. . The number of tumors were significantly lower in the animals that received turmeric in the diet and applied locally. Suggesting that curcumin and turmeric may have a plausible chemopreventive effect on oral precancerous lesions. Mechanism of chemoprotective and chemopreventive actions of Curcumin Curcuminoids are proven to have a dual-pronged mechanism of antioxidant action, viz., inhibiting the formation as well as propagation of free radicals.
Research methods
Patients received 8 grams of curcumin by mouth every day for two months. Maintenance therapy was continued at the same dose and schedule until the disease progressed
Anti Inflammatory Action
Curcumin‘s potential benefits are so comprehensive and extensive, that we should all be taking it. A recent search of the Excerpta Medica database found no less than 149 citations referring to the medical benefits of curcumin. Studies show it inhibits prostaglandin production and stimulates the creation of cortisol which relieves inflammation. Studies concluded that curcuminoids significantly suppress TPA-induced oxidative stress via both interference with infiltration of leukocytes into the inflammatory regions and inhibition of their activation. Curcumin is marketed widely in the Western world as a dietary supplement for the treatment and prevention of a variety of disorders, including arthritis. Studies conducted found that curcuminoid extract inhibits activation of NF-KB suggesting that curcumin shares the same mechanism of action as anti-arthritic pharmaceuticals under development that target NF-KB. It also suggests that turmeric may have a use in other inflammatory disorders, such as asthma, multiple sclerosis and inflammatory bowel disease.
In addition to preventing joint inflammation, Dr. Funk's study shows that the curcuminoid extract blocked the pathway that affects bone resorption. Noting that bone loss associated with osteoporosis in women typically begins before the onset of menopause, she has begun work on another NIH-funded study to determine whether turmeric taken as a dietary supplement during perimenopause can prevent bone loss and osteoporosis. Both of the studies are supported by the National Center for Complementary and Alternative Medicine (NCCAM) and the Office of Dietary Supplements (ODS), both of the NIH. One study found that Curcumin can prevent the progression of degenerative diseases such as atherosclerosis. Atherosclerosis is characterized by oxidative damage which affects lipoproteins, the walls of blood vessels and subcellular membranes. Thus the ethanol water extract of Curcuma longa (containing curcuminoids), is potentially useful in the prevention of atherosclerosis
Wound Healing
Turmeric has been traditionally used in wound healing. Tissue repair and wound healing are complex processes that involve a series of structural changes in the tissue. These include inflammation, granulation, and remodeling of the tissue. The effect of curcumin on wound healing was studied and found to heal more rapidly as compared to untreated controls. Several areas within the dermis showed extensive development of new blood vessels, and greater collagen deposition in curcumin-treated wounds. Cell injury by oxidative stress has been implicated in renal epithelial cell destruction during the progression of kidney diseases.
Immunomudulation
Many of the beneficial actions of natural compounds may be attributed to their immunomodulating effects. The effects of dietary curcumin on three major types of immune function were examined in rats. Cell proliferation was reduced by almost 50% after 24 hrs. A significant study suggested that curcumin may have a potential effect on controlling allergic diseases. These results have relevance in the potential use of curcumin in the management of bronchial asthma.
Curcumin & Alzheimer’s Disease
Our group has tested curcumin in several models for Alzheimer’s and found that it not only reduces oxidative damage and inflammation (as expected), but also reduces amyloid accumulation and synaptic marker loss and promotes amyloid phagocytosis and clearance. Curcumin worked to prevent synaptic marker and cognitive deficits caused by amyloid peptide infusion and abeta oligomer toxicity in vitro. Our work on curcumin indicates that curcumin stimulates immune cells to clear Alzheimer’s plaque. UCLA/VA Researchers found that curcumin may help the immune system clear the brain of amyloid beta, which form the plaques found in Alzheimer's disease.
Curcumin & Green Tea
The synergism between natural antioxidants as tumor inhibitors implies that different antioxidants are active at different stages of cell growth and proliferation, offering greater protection when used in combination than when used singly. The synergistic chemopreventive effects of the potent antioxidant fraction from green tea (-) epigallocatechin gallate and curcumin was examined in an in vitro study on normal, premalignant and malignant human oral epithelial cells. The effective doses required to inhibit the proliferation of cancer cells fell significantly when the antioxidants were used in combination. The combination reduced the ED value by 4.4 to 8.5 fold as compared to EGCG alone and 2.2 to 2.8 fold as compared to curcumin alone. This synergistic effect is attributed to the differential growth inhibition mechanisms of EGCG and curcumin. The compounds are active at different stages of cell growth and proliferation.
Boswellin
Reduce Joint Pain and Arthritis
Millions of Americans suffer from bone and joint problems ranging from osteoporosis to arthritis. "Many people associate arthritis with the process of aging; they assume aches and pains are an inevitable part of aging, when in fact it is not a natural part of aging." The good news is that unlike aspirin and other nonsteroidal, anti-inflammatory drugs commonly prescribed for arthritis, natural remedies do more than mask painful symptoms … and without any side effects. Even more dramatic, X-rays show that arthritis damage can actually be reversed. You should be aware of some supplements that assist in rebuilding cartilage and have powerful anti-inflammatory effects such as Boswellin and curcumin and also alleviate arthritis. This confirms what nutritional scientists and thousands of supplement users have been saying for years: Natural supplements enable you to prevent, improve, and even reverse the debilitating effects of arthritis without dangerous drugs or surgery,
Boswellin is a derivative of the Boswellia serrata tree that grows in India. It's also known as Boswellia or "Indian frankincense. Unlike modern NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen and aspirin, Boswellin doesn't cause stomach irritation or other harmful side effects. An important recent study of 175 patients with rheumatic and arthritic symptoms showed promising results. Within four weeks of taking Boswellin, 122 patients reported reduced stiffness and inflammation. Boswellin also appeared to be particularly effective in alleviating lower back pain.11 Mickey S., a 55-year-old back patient in Illinois reports: "I've been hospitalized three times with back pain so intense I couldn't even sit up. The drugs and injections they gave me in the hospital helped while I was there, but they also made me so groggy, I couldn't think straight much less work. So they weren't the answer." "Since being hospitalized, I've tried a half-dozen different supplements, and found Boswellin to be the most effective. Most of the time, the pain is simply gone. For the first time in five years, I can forget about my back and get on with my life."
Conclusion
It's a relief to know that you don't have to rely on pain-reducing drugs that are irritating to the stomach, and may have other side effects. These natural supplements have been proven safe and effective for alleviating pain and inflammation … and the best news is that they offer the long term benefits of helping restore and repair damaged tissues, and support healthy joints and cartilage. Anti Microbial properties Helicobacter pylori is implicated as an etiologic agent in the development of chronic gastritis, duodenal ulceration, and gastric adenocarcinoma.
Curcumin, which inhibits NF-kappaB activation, was found to also completely suppress IL-8 induction by H. pylori, thereby suggesting the potential use of curcumin in the control of pathogenicity of H. pylori. Curcumin has been reported to inhibit the replication of human immunodeficiency virus. A recent study suggests that curcumin inhibits the virus-cell fusion stage in the replication cycle of HIV. The inhibitory activity of curcumin against HIV-1 integrase has also been reported with certain curcumin analogs such as dicaffeoylmethane and rosmarinic acid being useful as well, in this regard.
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Curcumin Can Used for
Vitamin D, curcumin may help clear amyloid plaques found in Alzheimer's disease | Cancer | Joint Pain joint health| Arthritis | anti cancer potential of curcumin | Natural immune defense system | supports lean body mass | maintain healthy Cholesterol | Ant-Aging/Cleansing | skin | weight loss | Diabetics from inflammation-related health complications | dietary supplements
curcumin is the majore component of turmeric extract and contains many powerful antioxidant and anti inflammatory compounds. curcumin works at cellular level and support colon health experts neuro protective activity and helps maintain a healthy cardiovascular system
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Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). The other two curcuminoids are desmethoxycurcumin and bis-desmethoxycurcumin. The curcuminoids are polyphenols and are responsible for the yellow color of turmeric
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Turmeric (Curcuma Longa) Haldi Turmeric (Curcuma longa) family of Zingiberaceae) a Perennial herbal plant, native to India and known as Haldi Anti-inflammatory
Turmeric (Curcuma longa) family of Zingiberaceae) a Perennial herbal plant, native to India and known as Haldi.
The herbal preparations are derived from the plant's yellowish-orange root, which is also used as a dye. dietary supplements Tumeric, prime component of curry powders, used as a spice to flavour many types of food
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